Life Extension Mix formula contains 190 mg niacin per daily dose, which means you'll be getting a little over 63 mg with each meal. Life Extension Mix with Extra Niacin, however, contains 862 mg niacin per daily dose, which is 287 mg per meal. Extra niacin is generally used by people concerned with cholesterol. This high level of niacin creates what is called a niacin flush, a harmless sensation of warmth, heat and tingling accompanied by a temporary reddening of the skin that can last an hour or more. The niacin flush is usually not experienced by people who choose the regular formula Life Extension Mix.
High levels of niacin such as those in Life Extension Mix with Extra Niacin should be used with caution by those with liver disease. Consult your physician if you have an elevation of liver enzymes or enlargement of the liver.